Blood Cells Generated by Modified Stem Cell Differentiation

Researchers have identified two transcription factors that induce stem cells to differentiate into blood cells.

A research group led by Dr. Igor Slukvin, MD PHD, from University of Wisconsin-Madison has identified two transcription factors responsible for the differentiation of stem cells into numerous types of white and red blood cells.  The team made use of messenger RNA to overexpress the two transcription factors, which allowed them to generate 30 million blood cells for every million stem cells, without the use of a virus or altering the genetic structure of the blood. Continue reading