Listen to Your Gut – “Mini-Stomachs” Built In-Vitro from Stem Cells.

Scientists have engineered cellular clusters that mimic the functions of the stomach.

Scientists at the Cincinnati Children’s Hospital Medical Centre have induced adult stem cells to differentiate into small clusters of gastric tissue that replicate the functions of the human stomach.  The lab-made structures, known as “mini-stomachs”, were created by replicating the chemical pathways of early stage stomach development of stem cells in a petri dish.   Continue reading

Stem Cells Grow Human Intestines Successfully

Scientists have engineered human intestinal tissue through the use of stem cells.

Researchers from the Cincinnati Children’s Hospital Medical Centre have successfully grown functional human intestinal tissues by utilizing stem cells. After stimulating the stem cells with a “molecular cocktail” of chemicals and growth factors, the team observed as the cells developed into the mucosal lining and muscle layers, while exhibiting digestive functions such as nutrient uptake and responding to molecular signals. Continue reading

Esophagus Engineered with Stem Cells In-Vivo.

Scientists have utilized stem cells to engineer an esophagus without exogenous growth factors.

Researchers from the Saban Research Institute of Children’s Hospital Los Angeles have grown esophageal tissue in vivo (in the body) from stem cells without the use of exogenous growth factors.  In an animal model, the scientists transplanted stem cells, as well as a simple biodegradable scaffold, and relied on the stem cells’ ability to migrate towards the tissue in need of repair.  The cells then differentiated into the epithelial, muscle, and nerve cells to develop a healthy esophagus. Continue reading

Lab-Grown Kidney Moves Medicine One Step Closer to Organ Regeneration

Thousands of people die each year waiting for an organ donor to save their lives.

Research coming forth each day is revealing that  the promise of regenerative medicine,  may one day aid in preventing needless loss of life due to lack of available donors.

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