Ophthalmologists James L Funderburgh, Ph.D. and Fatima Syed-Picard, Ph.D. from the University of Pittsburgh have devised a method for treating corneal blindness by utilizing dental pulp stem cells. The researchers harvested the stem cells from molars discarded during routine extraction and induced the cells to differentiate into keratocytes [corneal cells]. They then seeded the cells onto a nanofiber scaffold, allowing them to grow into fully developed, functional corneas capable of restoring eyesight. Continue reading
A research team led by Dr. Songtao Shi from the Herman Ostrow School of Dentistry of USC has discovered that mesenchymal stem cells [MSCs] found in the gums are able to regulate the body’s immune system to treat inflammatory diseases. In an animal model suffering from colitis [an inflamed condition of the colon], the scientists were able to transplant these gingival MSCs, significantly reducing the inflammation. Continue reading
A team of researchers led by Professor Andrew Lotery at Southampton General Hospital have discovered a source of retinal stem cells on the surface of the eye. If scientists can harvest these readily accessible stem cells, convert them to light-sensitive cells, and then transplant them back into the eye, the cells could provide new treatments for age-related macular degeneration [AMD].
Currently, AMD is the leading cause for blindness in patients over the age of 50, and there is no known cure. However, the discovery of stem cells on the retina could facilitate a new method for scientists to replenish the light-sensitive cells in a patient’s eyes without the risk of rejection by the immune system, presenting a new potential treatment for the disease.
Although AMD tends to affect patients later on in life, the higher regenerative abilities of younger stem cells are preferable over older ones for medical therapies. One way to assure access to the enhanced regenerative abilities of your own stem cells is to preserve them while they are still young, so that they can be used later in life in emerging regenerative therapies. Today, preserving your own stem cells, also known as autologous stem cells, is simple and affordable for families. To learn how you can preserve your own valuable stem cells through non-invasive and effective methods, please visit StemSave or call 877-783-6728 (877-StemSave) today.
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The Future of Regenerative Medicine is Now™.
Neuroscientist Dr. Karen Aboody, M.D. and Oncologist Dr. Jana Portnow, M.D. from City of Hope Hospital are set to begin a phase 1 clinical trial for a method of delivering chemotherapy treatments to glioblastoma [aggressive brain tumors] with modified neural stem cells. The scientists plan to capitalize on the stem cells’ innate ability to seek out invasive tumors by loading the cells with a chemotherapeutic protein and then injecting them into the brain. Continue reading
Today, stem cells are rightfully perceived as the future of regenerative medicine, set to bring the marvels of science fiction into reality. But in looking ahead at all of the promise that stem cells hold for the future, it becomes easy to miss the scientific advances made to date for the millions of people around the world suffering from disease, trauma, and injury. Thus, today marks Stem Cell Awareness Day: a global celebration of stem cell research coordinated to highlight the treatments and therapies currently in development to create personalized regenerative therapies for patients. Continue reading
Researchers at the National Institute for Dental and Craniofacial Research have developed a method of utilizing autologous [the patient’s own] dental stem cells to regenerate damaged or decayed teeth. In an animal model, as well as human cells in vitro [in a lab], the scientists treated the damaged teeth with low-intensity lasers, which prompted the stem cells located in the dental pulp to differentiate and grow into new, healthy dentin tissue. Continue reading
A team of medical researchers at Saint Luc University Clinic have developed a method of repairing bones utilizing autologous [the patient’s own] stem cells. The process involves harvesting the stem cells from the patient, differentiating the stem cells in-vitro to grow bone, pairing the cells with a scaffolding matrix and then molding the material to repair damaged or diseased bone within the patient. Continue reading
In a recent study supported by the National Institutes of Health, stem cells extracted from baby teeth were differentiated into neural cells. The success of the study demonstrates that teeth provide a non-invasive and accessible means for researchers to obtain and grow patient specific neural tissue to study autism spectrum disorders [ASD] and other neurological disorders. This is in contrast to the recovery of stem cells from other sources – such as a skin biopsy, that are both invasive, more costly and less advantageous in the study of neural related disorders. Continue reading
Researchers at UMass Medical School use human stem cells to ‘shut down’ the chromosomes causing Down syndrome. The lead researcher, Jeanne B. Lawrence, a professor of cell and developmental biology at UMass Medical School, explained, “Our hope is that for individuals living with Down syndrome, this proof-of-principal opens up multiple exciting new avenues for studying the disorder now, and brings into the realm of consideration research on the concept of ‘chromosome therapy’ in the future”. The treatment seeks to address the root cause of the disease as opposed to merely mitigating the symptoms of the disease.
Scientists at the University of California Davis’ Institute for Regenerative Cures are utilizing mesenchymal stem cells [the same type of stem cells found in teeth] to develop a new therapy that targets the genetic abnormality in Huntington’s disease. The principal investigator of the study, and the director of UC Davis stem cell program and the UC Davis Institute for Regenerative Cures, Jan Nolta said, “Our team has made a breakthrough that gives families affected by this disease hope that genetic therapy may one day become a reality.” The treatment seeks to address the root cause of the disease as opposed to merely mitigating the symptoms of the disease.