Dental Stem Cells Differentiated into Brain-like Cells for Stroke Patients

Scientists have discovered the ability of dental pulp stem cells to grow into brain-like neurons.

Researchers from the University of Adelaide, led by Dr. Kylie Ellis, have discovered that dental pulp stem cells [DPSC] have the ability to differentiate into complex networks of cells closely resembling neurons found in the brain.  According to Dr. Ellis, “Stem cells from teeth have great potential to grow into new brain or nerve cells, and this could potentially assist with treatments of brain disorders, such as stroke.” She goes on to say “ultimately, we want to be able to use a patient’s own stem cells for tailor-made brain therapy that doesn’t have the host rejection issues commonly associated with cell-based therapies. Another advantage is that dental pulp stem cell therapy may provide a treatment option available months or even years after the stroke has occurred.”  Current drug treatment therapies for stroke victims must be administered almost immediately following the stroke – within hours.  This severely limits their application as most stroke victims don’t have access to these treatments within that timeframe. Continue reading

Paralysis Treatment Utilizes Stem Cells

Stem Cell transplants have been found to regenerate motor neurons to restore muscle capability after paralysis.

Professor Linda Greensmith and her team of researchers from University College London and King’s College London have utilized stem cells to return muscle function to patients paralyzed by nerve damage or spinal cord injury.  In a paralyzed animal model, the scientists observed transplanted stem cells growing along the injured neurons to restore motor capability to disabled muscle.  Blue light pulses were then used to control the newly restored muscle movement. Continue reading

Vaginal Implants Grown Utilizing Autologous Stem Cells

Stem Cells were utilized to create lab-engineered vagina implants for patients suffering from MRKH syndrome.

Researchers from the Wake Forest Baptist Medical Center’s Institute for Regenerative Medicine have successfully grown and implanted vaginal organs into four teenage girls born with MRKH Syndrome, a rare condition in which the vagina is undeveloped. The scientists extracted the patient’s own stem cells and placed them onto a biodegradable scaffold of a vagina.  The scaffolds were then implanted into the patient’s pelvis, and gradually the stem cells differentiated into a permanent, functional vagina. Continue reading

Doctors Recommend Banking Stem Cells Following Hip Replacement Surgery

A source of stem cells has been discovered in the discarded tissue resulting from hip surgery.

Researchers from the UNSW Graduate School of Biomedical Engineering, Ludwig Maximilians University, Case Western Reserve University, and the Cleveland Clinic have identified a source of autologous [the patient’s own] stem cells, called periosteum-derived stem cells [PDSC], which reside in the discarded tissue resulting from hip replacement surgery. Continue reading

Spinal Cord Injury Stem Cell Treatment Enters Clinical Trials.

A new treatment aims to treat spinal cord injuries by injecting stem cells into the spinal cord.

A medical team from the University of Calgary is now recruiting candidates to participate in the phase one clinical trial for a new stem cell therapy that aims to treat spinal cord injuries.  The researchers plan to inject stem cells into the spinal cord two sites above and two sites below the point of injury to recreate lost or damaged tissue. Continue reading

Heart Failure Treatment Utilizing Stem Cells.

Columbia researchers have developed a scaffold that will allow stem cells to repair heart damage.

A team of researchers led by Dr. Gordana Vunjak-Novakovic [a member of StemSave’s Scientific Advisory Council] has engineered a scaffold to facilitate the regeneration of heart muscle through the use of adult stem cells.  In an animal model, Vunjak-Novakovic and her team created a scaffold using biodegradable chitosan and carbon nanofibers, infusing it with stem cells to provoke the regeneration of beating cardiomyocytes. Continue reading

Prostate Cancer Study Utilizes Stem Cells.

Researchers have used stem cells to identify a marker specific to cancer cells that could lead to new prostate cancer treatments.

Molecular Biologists from Genentech, Inc., in California have utilized stem cells to better understand the advent and growth of prostate cancer.  The researchers discovered a marker specific to cancerous cells that, when used as a therapeutic target, could lead to the development of new prostate cancer treatments. Continue reading

Longevity Expert Dr. Vincent Giampapa Discusses Stem Cells on the Today Show

Dr. Vincent Giampapa, featured in Steven Hawking’s ‘Stem Cell Universe’ [recently broadcast on the Science Channel] was interviewed on the Today Show – Australia.  According to Dr. Giampapa, the key to longevity and maintaining your health are your stem cells.  New advancements in anti-aging technology are heavily reliant on autologous [the patient’s own] stem cells to reduce the degenerative effects of aging. Continue reading

Mesenchymal Stem Cells Prevent Long-Term Damage after Traumatic Brain Injury

Stem Cells are used to regulate inflammation after a TBI.

A study from the University of Texas Health Science Center has discovered a novel function of mesenchymal stem cells in preventing long-term brain damage and inflammation in patients following traumatic brain surgery.  MSCs injected into TBI-mice actually travelled to the spleen to regulate the body’s inflammatory response to the trauma and preserve brain function. Continue reading

Mind the Gap: “BioPen” Offers Personalized Bone Reconstruction

The Biopen “fills in” damaged bone with stem cells to facilitate bone regeneration.

Researchers at Melbourne’s St. Vincent Hospital and the University of Wollongong are engineering a device known as the “Biopen” to deliver stem cells to damaged or diseased bones. This novel method of stem cell therapy administers a mixture of jelly and stem cells into the damaged sections of the bone. The jelly is then UV-dried into a scaffolding to facilitate stem cell growth and bone regeneration.

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