Of Mice and Men: Human Stem Cells Utilized in Animal Model Treatment of MS Symptoms

Advancements in a breakthrough stem cell study may provide new treatment options for MS patients.

A team of researchers led by Professor Jeanne Loring of the Scripps Research Institute have advanced a potential treatment option for autoimmune diseases similar to multiple sclerosis by utilizing human stem cells to reregulate the immune system. In an animal model paralyzed by MS symptoms, the scientists differentiated human stem cells into early stage neural cells that, when transplanted into the spinal cords of the compromised mice, secreted proteins that halted the autoimmune attack and enabled the mice to walk and run again. Continue reading

Multiple Sclerosis Patients Reboot Immune System with Stem Cells

Biologists have successfully reset the self-destructive immune systems of Multiple Sclerosis patients by utilizing autologous stem cells.

In a recent publication, biologists in the Immune Tolerance Network have used autologous [the patient’s own] stem cells to refurbish the immune systems of Multiple Sclerosis [MS] patients to no longer favor autoimmunity. The ITN researchers suppressed the patients’ immune systems, transplanted the stem cells, and in a 12 month follow-up, identified key distinctions between the patients’ T-cells before and after the transplant, indicating that the procedure was a success. Continue reading