According to a recent study conducted by scientists at the Harvard Stem Cell Institute, stem cells may hold the key to replacing the body’s unwanted storage of white fat cells with calorie-burning brown fat cells. The researchers studied the stem cells that typically mature into white fat cells, and, after screening the effects of 1000 compounds on the cells, they found two that stimulate the stem cells to differentiate into brown fat cells instead. Continue reading
Scientists at the Cincinnati Children’s Hospital Medical Centre have induced adult stem cells to differentiate into small clusters of gastric tissue that replicate the functions of the human stomach. The lab-made structures, known as “mini-stomachs”, were created by replicating the chemical pathways of early stage stomach development of stem cells in a petri dish. Continue reading
Researchers from the Cincinnati Children’s Hospital Medical Centre have successfully grown functional human intestinal tissues by utilizing stem cells. After stimulating the stem cells with a “molecular cocktail” of chemicals and growth factors, the team observed as the cells developed into the mucosal lining and muscle layers, while exhibiting digestive functions such as nutrient uptake and responding to molecular signals. Continue reading
Apceth, a leader in the development of stem cell treatments, has won approval for a Phase I/II multicenter clinical trial evaluating an autologous mesenchymal stem cell (MSC) therapy for gastrointestinal cancer. The treatment involves the utilization of the patient’s own stem cells to combat and destroy cancerous cells and is designed to enable highly localized treatments.