Medical researchers from Keele University and Nottingham University have integrated remote controlled magnetic nanoparticles to incite the differentiation of stem cells into new bone tissue for the treatment of bone diseases, disorders, and injuries. In pre-clinical trials, the nanoparticles were coated with proteins that stimulate the stem cells, and then delivered directly to the damaged tissue via an external magnetic field. Continue reading
Scientists led by Dr. Craig Mello of The University of Massachusetts have developed a genetic tool – CRISPR [clustered regularly interspaced short palindromic repeats] – to revolutionize the way stem cells are applied to treat genetic diseases, such as sickle cell or thalassemia. CRISPR aims to expedite and improve upon the process of translational genomics, in which the patient’s stem cells are extracted, altered to repair the damaged gene, and then transplanted back to the patient. Continue reading
Complex chemical polymers are currently being developed by scientists at Stanford University to protect and support the proliferation of stem cells during spinal cord transplantation procedures. The gels are designed to provide padding for the cells during injection, while also varying in viscosity and the biochemical signals contained within to offer stem cells an optimal environment for differentiation. Continue reading
As reported on the front page of the New York Times Science section, clinical applications of stem cell based therapies are accelerating at a rate that will revolutionize the medical field in a matter of years. In the United States alone, there are currently over 4000 therapies in clinical trials for the treatment of heart disease, blindness, spinal cord injuries, diabetes, H.I.V., and other diseases, injuries, and traumas. Continue reading
Researchers at the University of California, San Diego are set to begin clinical trials to test the safety and effectiveness of a neural stem cell transplant designed to treat spinal cord injuries. In an animal model, the stem cells were able to regenerate the nerves across the site of injury, resulting in the restoration of mobility in the legs. Continue reading
Professor Linda Greensmith and her team of researchers from University College London and King’s College London have utilized stem cells to return muscle function to patients paralyzed by nerve damage or spinal cord injury. In a paralyzed animal model, the scientists observed transplanted stem cells growing along the injured neurons to restore motor capability to disabled muscle. Blue light pulses were then used to control the newly restored muscle movement. Continue reading
A team of researchers at the University of Illinois led by doctors Fei Wang, Qiuhao Qu, and JianJun Cheng, have developed a fast and efficient technique for differentiating stem cells into motor neurons. The researchers added critical signaling molecules and growth factors to the cells much earlier than previous methods, resulting in twice the amount of neurons derived from the cells in half the time. Continue reading
In a recent Phase II clinical study, researchers report that mesenchymal stem cells were successful in relieving chronic lower back pain. The scientists injected MSCs directly into the degenerating vertebral disks of patients suffering from lower back pain, resulting in an overall reduction in the mean pain score, improved function for at least 12 months, and a reduced need for further surgical and non-surgical treatment interventions.
Of the 6 million Americans suffering from debilitating back pain today, 3.5 million are affected by degenerative invertebral disk disease. The results of this clinical trial show that, instead of addressing the symptoms, mesenchymal stem cells are able to treat the source of the pain for long lasting relief. According to lead researcher, Dr. Tory McJunkin, M.D, “This study shows we are progressing toward major advances in pain medicine,”
Mesenchymal stem cells have the unique capacity to regenerate a multitude of different types of tissues – such as neurons, insulin producing pancreatic beta cells, bone, cartilage, and cardiomyocites amongst them. This Phase II study is just one example of the utility of stem cells in successfully treating conditions previously thought to be untreatable or treatable only through invasive options. To learn how to bank your own valuable stem cells to insure access to emerging regenerative therapies, visit www.stemsave.com or call 877-783-6728 877-StemSave) today.
A medical team from the University of Calgary is now recruiting candidates to participate in the phase one clinical trial for a new stem cell therapy that aims to treat spinal cord injuries. The researchers plan to inject stem cells into the spinal cord two sites above and two sites below the point of injury to recreate lost or damaged tissue. Continue reading
Dr. Peter Donovan, Dr. Hans Keirstead, Dr. Aileen Anderson, Dr. Brian Cummings, Dr. Frank LaFerla, Dr. Leslie M. Thompson, and Dr. Matthew Blurton-Jones of UC Irvine discuss the importance of stem cells and the current research taking place within their labs.