Atherosclerotic Lesions Prevented by MSCs

Stem cells were found to reduce plaque in patients with atherosclerosis.

According to new research from the National Yang-Ming University, mesenchymal stem cells [MSCs] hold the ability to limit atherosclerotic plaque formation, thereby preventing the onset of harmful endothelial lesions. The research team, led by Shih-Chieh Hung, transplanted MSCs into animal models with atherosclerosis and observed significant reduction in plaque formation. They also saw an increase in blood vessel dilation, which prevents further plaque development, indicating good endothelial health. Continue reading

Peripheral Artery Disease Treatment Utilizes Stem Cells

Scientists have devised a method of regenerating blood vessels by transplanting stem cells.

Researchers from the Indiana University School of Medicine have developed a potential therapy for peripheral artery disease by transplanting autologous [the patient’s own] stem cells.  In an animal model, the transplanted stem cells differentiated into new blood vessels, which then restored blood flow to damaged tissues in the body. Continue reading

Autologous Stem Cell Treatment for Peripheral Arterial Disease [PAD]

Peripheral Arterial Disease leg schematic

University Hospital’s Case Medical Center researchers are to begin evaluating the ability of the patient’s own stem cells [autologous stem cells] to prevent leg amputations in peripheral arterial disease.  PAD effects more than 5 million adults in the US alone.  Dr. Vik Kashyap, the leading researcher, explained, “This trial offers an opportunity to save a patient’s leg when there are no remaining options to improve blood supply.”

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