Bone Regeneration Technique Stimulates Stem Cells with Magnetic Nanoparticles.

Remote controlled nanoparticles may allow stem cells to regenerate bone tissue

Medical researchers from Keele University and Nottingham University have integrated remote controlled magnetic nanoparticles to incite the differentiation of stem cells into new bone tissue for the treatment of bone diseases, disorders, and injuries. In pre-clinical trials, the nanoparticles were coated with proteins that stimulate the stem cells, and then delivered directly to the damaged tissue via an external magnetic field. Continue reading

Stem Cells Immune to Damage from Leukemia Chemotherapy

Certain stem cells have been found to be immune to the bone-degenerative side effects of chemotherapy used against leukemia.

A research team, led by Dr. Eric Darling of Brown University, has found a potential source of stem cells to protect children with acute lymphoblastic leukemia against the adverse effects of the chemotherapy drug methotrexate (MTX).  Adipose-derived stem cells, which appear to be impervious to the bone-degenerative side effects of MTX, may allow children to undergo the chemotherapy treatment and then regain the lost bone tissue afterwards. Continue reading

Paralysis Treatment Utilizes Stem Cells

Stem Cell transplants have been found to regenerate motor neurons to restore muscle capability after paralysis.

Professor Linda Greensmith and her team of researchers from University College London and King’s College London have utilized stem cells to return muscle function to patients paralyzed by nerve damage or spinal cord injury.  In a paralyzed animal model, the scientists observed transplanted stem cells growing along the injured neurons to restore motor capability to disabled muscle.  Blue light pulses were then used to control the newly restored muscle movement. Continue reading

Spinal Cord Injury Stem Cell Treatment Enters Clinical Trials.

A new treatment aims to treat spinal cord injuries by injecting stem cells into the spinal cord.

A medical team from the University of Calgary is now recruiting candidates to participate in the phase one clinical trial for a new stem cell therapy that aims to treat spinal cord injuries.  The researchers plan to inject stem cells into the spinal cord two sites above and two sites below the point of injury to recreate lost or damaged tissue. Continue reading

Bone Reconstruction Technique Utilizes Autologous Stem Cells

Stem cells are allowing doctors to personalize treatments to repair damaged or diseased bone.

A team of medical researchers at Saint Luc University Clinic have developed a method of repairing bones utilizing autologous [the patient’s own] stem cells.  The process involves harvesting the stem cells from the patient, differentiating the stem cells in-vitro to grow bone, pairing the cells with a scaffolding matrix and then molding the material to repair damaged or diseased bone within the patient. Continue reading

Mesenchymal Stem Cells [MSC] Promote Nerve Regeneration

neurons

Researchers at Johns Hopkins University, Department of Plastic and Reconstructive Surgery find that mesenchymal stem cells [the type of stem cells found in teeth] promoted nerve regeneration in animal models [in this case – rodents] with paralyzing leg injuries.  According to the researchers, “Mesenchymal stem cells may be a promising add-on therapy to help damaged nerves regenerate.”  The study found that the rodents treated with their own stem cells responded best to the treatment. Those treated with donated cells from dissimilar rodent types – a situation most similar to human transplants – rejected their new limbs.

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