Blood Cells Generated by Modified Stem Cell Differentiation

Researchers have identified two transcription factors that induce stem cells to differentiate into blood cells.

A research group led by Dr. Igor Slukvin, MD PHD, from University of Wisconsin-Madison has identified two transcription factors responsible for the differentiation of stem cells into numerous types of white and red blood cells.  The team made use of messenger RNA to overexpress the two transcription factors, which allowed them to generate 30 million blood cells for every million stem cells, without the use of a virus or altering the genetic structure of the blood.

Dr. Slukvin’s protocol has the potential to enable  scientists to safely create a variety of white or red blood cells that can be incorporated into clinical therapies for patients suffering from blood disorders or blood loss.  Further, the approach of manipulating genetic mechanisms to induce stem cell differentiation may be applicable to other cell types in the body, such as the cells in the heart, pancreas, and brain.

Dr. Slukvin’s research is an example of how scientists are gaining insights that will facilitate more effective treatments leading to better outcomes.  To learn more about the value of preserving your own mesenchymal stem cells for use in future therapies and how to bank your own stem cells through a non-evasive and affordable method by recovering your dental pulp stem cells, visit StemSave or call 877-783-6728 (877-StemSave) today.



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