Multiple Sclerosis Patients Reboot Immune System with Stem Cells

Biologists have successfully reset the self-destructive immune systems of Multiple Sclerosis patients by utilizing autologous stem cells.

In a recent publication, biologists in the Immune Tolerance Network have used autologous [the patient’s own] stem cells to refurbish the immune systems of Multiple Sclerosis [MS] patients to no longer favor autoimmunity. The ITN researchers suppressed the patients’ immune systems, transplanted the stem cells, and in a 12 month follow-up, identified key distinctions between the patients’ T-cells before and after the transplant, indicating that the procedure was a success. Continue reading

Human Lungs Successfully Grown in Lab via Stem Cells

Scientists may have found a solution for immune rejection of lung transplants.

Researchers from the University of Texas Medical Branch have successfully grown human lungs in vitro [in a lab] by utilizing stem cells.  The team of scientists, led by Dr. Michael Riddle, used a donated lung to engineer a scaffold outlining the lung’s architecture.  Then, they seeded the scaffold with stem cells from the donor’s complementary lung to create a complete, functional, and healthy lung.  Continue reading

Growing Organs With Your Own Stem Cells

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A research team led by Doctor Alexander Seifalian at University College London is currently creating custom lab-grown organs and body parts for patients utilizing autologous [the patient’s own] stem cells.  The scientists have engineered a polymer material that they mold into the shape of an organ in need, infuse with the patient’s stem cells, and then transplant back onto the patient’s body.   Continue reading

Dental Stem Cells Fill In For Root Canal Therapy

A new alternative procedure to root canal therapy utilizes stem cells to restore the root canal back to health.

Doctors at the All India Institute of Medical Sciences have developed a novel stem cell therapy called “SealBio” to replace traditional root canal treatments.  SealBio eliminates the need to clean, shape, and fill the tooth with artificial sealer cement by inducing the stem cells of the root to regenerate adult tissue as a natural biological seal. Over time, this technique can even restore the root canal back to health.       Continue reading

Vaginal Implants Grown Utilizing Autologous Stem Cells

Stem Cells were utilized to create lab-engineered vagina implants for patients suffering from MRKH syndrome.

Researchers from the Wake Forest Baptist Medical Center’s Institute for Regenerative Medicine have successfully grown and implanted vaginal organs into four teenage girls born with MRKH Syndrome, a rare condition in which the vagina is undeveloped. The scientists extracted the patient’s own stem cells and placed them onto a biodegradable scaffold of a vagina.  The scaffolds were then implanted into the patient’s pelvis, and gradually the stem cells differentiated into a permanent, functional vagina. Continue reading

Motor Neuron Development Accelerated by New Stem Cell Technique

A new procedure in differentiating stem cells will accelerate advances in treating neurological diseases.

A team of researchers at the University of Illinois led by doctors Fei Wang, Qiuhao Qu, and JianJun Cheng, have developed a fast and efficient technique for differentiating stem cells into motor neurons.  The researchers added critical signaling molecules and growth factors to the cells much earlier than previous methods, resulting in twice the amount of neurons derived from the cells in half the time. Continue reading

New Stem Cell Therapy Heard Loud and Clear

A new understanding of stem cell pathways can accelerate advances in reversing hearing loss.

Scientists from Harvard Medical School and the Massachusetts Eye and Ear Infirmary have found a signaling pathway that, when blocked, prevents the onset of noise-induced hearing loss and deafness.  In an animal model, the inhibition of the pathway allowed stem cells in the inner ear to differentiate and regenerate sound-sensing hair cells, which are integral to the ability to hear. Continue reading

Muscle Degeneration Reversed Through Discovery of Stem Cell Pathways

A new discovery in stem cell differentiation could lead to new treatments for muscle-wasting diseases.

Recent research from the University of Colorado Boulder has identified two stem cell signaling pathways that are directly related to the age-related degeneration of muscle tissue and the onset of a variety of muscle-wasting diseases, such as muscular dystrophy and sarcopenia.  By altering these pathways, the investigators were able to enhance muscle stem cell renewal and improve muscle regeneration. Continue reading

Genetic Diseases Decoded Utilizing Stem Cells

A new method of studying stem cells will lead to new translational genomics treatments for patients suffering from genetic diseases.

A team of Gladstone research scientists has utilized stem cells to develop a new gene-editing technique for inducing and studying rare genetic mutations linked to disease.   The technique, called TALENs, presents an opportunity for patients with genetic disorders to use their own stem cells to identify their specific genetic mutations. Continue reading