Mind the Gap: “BioPen” Offers Personalized Bone Reconstruction

The Biopen “fills in” damaged bone with stem cells to facilitate bone regeneration.

Researchers at Melbourne’s St. Vincent Hospital and the University of Wollongong are engineering a device known as the “Biopen” to deliver stem cells to damaged or diseased bones. This novel method of stem cell therapy administers a mixture of jelly and stem cells into the damaged sections of the bone. The jelly is then UV-dried into a scaffolding to facilitate stem cell growth and bone regeneration.

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The Nose Knows – Intranasal Delivery of Stem Cells to Treat Neurological Disease

Intranasal delivery may facilitate stem cell treatment to the brain.

Researchers from StemGenex have announced plans to treat neurological diseases utilizing intranasal [through the nose] delivery of mesenchymal stem cells.   The current research indicates stem cells were able to pass the blood brain barrier by travelling up the olfactory nerves, providing a novel approach to stem cell delivery. Such an approach would represent a significant advancement in regenerative medicine. Continue reading

Autologous Stem Cells Promote Proper Bone Healing

Autologous stem cells eliminate the risk of bone loss and infection in hard to heal bone fractures

A study team from Kobe University Graduate School of Medicine in Japan has developed a treatment for hard to heal bone fractures. The treatment makes use of autologous [the patient’s own] stem cells to promote proper healing in fractures that fail to heal on their own. Continue reading

Never Too Old For Stem Cells

Emerging regenerative therapies should be available to patients of all ages.

A recent study from the Dana-Farber Cancer Institute has proven that stem cell transplants in myelodysplastic syndrome (MDS) patients were equally successful for patients age 71-74 as it was for patients age 60-65.  According to Dr. Gregory Abel, an oncologist at Dana-Farber, “This is good evidence that age alone should not limit who should get a [stem cell] transplant for MDS.” Continue reading

Researchers Utilize Stem Cells to Study Parkinson’s Disease

Stem Cells could lead to personalized treatments for diseases involving genetic mutations

Recently, researchers team from Sanford-Burnham’s Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research and MIT’s Whitehead Institute for Biomedical Research used stem cells from patients with Parkinson’s disease to show that a genetic mutation is partly responsible for cell death in the patients’ nervous system.  This study exhibits a novel ability of stem cells to act as a model through which researchers can better understand diseases and develop better outcomes. Continue reading

Unique Properties of Mesenchymal Stem Cells Promotes Growth of New Blood Vessels

MSCs can promote other stem cells into organizing into new tissues, organs, and vascularization.

Researchers at University of Illinois at Chicago have discovered an ability of mesenchymal stem cells [the type of stem cells found in teeth] to facilitate the growth of new blood vessels.  MSCs promotion of vascularization is critical, not only for the repair of damaged tissue and organs, but for the development of new organs as well. Continue reading

Cartilage Regeneration Method Promises Rapid Knee Repair

Stem Cells could make knee cartilage repair more convenient and 75% less expensive.

Researchers in the Netherlands at UMC Utrecht have developed a method to combine two chondrocyte knee repair surgeries into one using mesenchymal stem cells (MSCs).  The new procedure takes chondrocytes (cells found in cartilage) from the patient, mixes them with specialized MSCs, and then implants them back into the damaged area of the knee.  The stem cells help regenerate the cartilage, while the patient’s own cells avoid an immune response when implanting the mixture. Continue reading

Stem Cells Utilized to Generate “Mini-Kidney”

Three-Dimensional kidneys will allow doctors to better study kidney diseases.

Researchers at the Salk Institute for Biological Studies have developed a method for generating a small, three-dimensional kidney structure thus enabling researchers to better understand various kidney diseases and to enhance the development of more personalized, effective treatment options. Kidney disease is a significant health issue with Chronic Kidney Diseases affecting one in every 10 American adults. Continue reading