Hypoxic-Ischemic brain injury can be caused by a number of ailments including cardiac arrest (heart attack), respiratory arrest, incomplete suffocation and more. The incidence in the United States of hypoxic-ischemic brain injuries is 1-8 in every 1000 births. Researchers at Nagoya University have used stem cells from human exfoliated deciduous teeth (SHED) to treat neonatal mice with hypoxic-ischemic brain injuries. They have found that this treatment leads to neurological and pathophysiological recovery of these injuries. These finding indicate that SHED may be utilized in the future for a novel neuroprotective therapy for hypoxic-ischemic brain injuries.